HCID 23369594, compound → HCID 23369663, compound

HRID 1900843Notes

Reaction equation

HRID 1900843 reaction equation
[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6]2[C:11]([CH:12]=1)=[C:10]([O:13]CC(C)=C)[CH:9]=[CH:8][C:7]=2[CH3:18])[CH3:2]>C(Cl)(Cl)Cl.CO.CCCCCC>[CH2:1]([C:3]1[C:4](=[O:19])[NH:5][C:6]2[C:11]([CH:12]=1)=[C:10]([OH:13])[C:9]([CH2:12][C:3]([CH3:4])=[CH2:1])=[CH:8][C:7]=2[CH3:18])[CH3:2]

Participants

3

Reactant 1

HCID 23369594HCID 23369594, compound

Product 1

HCID 23369663HCID 23369663, compoundYield 150.8%

Reagents, catalysts & solvents 1

HCID 22285155HCID 22285155, compoundSolvent

Procedure

Using 3-ethyl-5-(2-methyl-2-propenyl)oxy-8-methylcarbostyril (0.94 g, 3.66 mmol), the procedure of Reference Example 32 was followed (reaction, post-treatment, and recrystallization from chloroform-methanol-n-hexane) to obtain 710 mg of the title compound as pale yellow crystals (75.5%).

Sources & evidence

ORD record
ord-a2d7dabf41ac4b96a46ee2ca01b5ec45
Source dataset
uspto-grants-1996_11
Patent number
US05576324

Reaction notes

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