Allyl iodide → HCID 23369687, compound

Participants

Reaction Conditions

Reaction Steps

5-Hydroxy-3-isopropyl-8-methylcarbostyril (1.60 g, 7.37 mmol) was dissolved in dimethylformamide (30 ml), to which potassium carbonate (2.50 g, 18.1 mmol) and allyl iodide (0.71 ml, 7.76 mmol) were added. The mixture was stirred at 70° C. for 90 minutes. The reaction mixture was condensed under reduced pressure. The resultant residue was extracted from chloroform-water. The organic phase was washed with saturated aqueous NaCl solution, dried, and condensed under reduced pressure. The residue was recrystallized from chloroform-ether to obtain 1.85 g of the title compound as pale yellow powdery crystals (97.9%).

Provenance & Evidence