HCID 23369654, compound → HCID 23369772, compound

HRID 1900855Notes

Reaction equation

HRID 1900855 reaction equation
[CH:1]([C:4]1[C:5](=[O:20])[NH:6][C:7]2[C:12]([CH:13]=1)=[C:11]([O:14]CC(C)=C)[CH:10]=[CH:9][C:8]=2[CH3:19])([CH3:3])[CH3:2]>C(OCC)(=O)C.CCCCCC>[OH:14][C:11]1[C:10]([CH2:3][C:1]([CH3:4])=[CH2:2])=[CH:9][C:8]([CH3:19])=[C:7]2[C:12]=1[CH:13]=[C:4]([CH:1]([CH3:2])[CH3:3])[C:5](=[O:20])[NH:6]2

Participants

3

Reactant 1

HCID 23369654HCID 23369654, compound

Product 1

HCID 23369772HCID 23369772, compoundYield 185.3%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 3-isopropyl-8-methyl-5-(2-methylallyl)oxycarbostyril (1.0 g, 3.7 mmol), the procedure of Reference Example 65 was followed (reaction, post-treatment, recrystallization from ethyl acetate-hexane). 930 mg of the title compound was obtained as colorless needles (92.6%).

Sources & evidence

ORD record
ord-f8aa892939524b599f2d78a3055d5fec
Source dataset
uspto-grants-1996_11
Patent number
US05576324

Reaction notes

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