HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 57325182, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 6-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 10420726 | — |
| Reactant | (2s)-Glycidyl indol-4-yl ether | HCID 10943254 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 57325182 | HCID 57325182 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Example 1 using (S)-(+)-4-(oxiranylmethoxy)-1H-indole (0.389 g, 2.05 mmol) and 6-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.400 g, 1.87 mmol) using ethanol as reaction solvent. Yield 0.260 g (35%) as an orange foam. mp 99°-103° C. (dec). FDMS m/e=401 (M+ of free base). α[D]589 =+5.1 (c=0.98, dimethylsulfoxide).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576321 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-ba72dc283e3d4d048158c0df7de35c68 |
| Source note | uspto-grants-1996_11 |