HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperonylamine → 6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperonylamine | HCID 2723901 | — |
| Reactant | 6,7-dichloro-1H-indole | HCID 12272802 | — |
| Product | 6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 18545981 | — |
Reaction Steps
The title compound was prepared in a fashion similar to that described in Preparation 30 from 6,7-dichloroindole (1.4 g, 7.5 mmol) and 4-piperidone hydrochloride hydrate (2.3 g, 15 mmol). The product was isolated as a white solid. Yield 1.8 g (89%). mp 252°-254° C. FDMS m/e=268 (M+ of free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576321 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-50c10428865c4719a6c5fed374a9256c |
| Source note | uspto-grants-1996_11 |