HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylheptylamine → 1-(4-Fluoro-2-nitrophenyl)-3-heptyl-3-methylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylheptylamine | HCID 93190 | — |
| Reactant | Phenyl 4-fluoro-2-nitrophenylcarbamate | HCID 23370075 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 1-(4-Fluoro-2-nitrophenyl)-3-heptyl-3-methylurea | HCID 23370111 | — |
Reaction Steps
Phenyl 4-fluoro-2-nitrophenylcarbamate (0.70 g) and N-methylheptylamine (0.33 g) were dissolved in xylene (5 ml) and the solution was heated under reflux for 2 hrs. The solvent was distilled off and the residue was purified by a silica gel column chromatography (hexane:ethyl acetate=3:1) to give 1-(4-fluoro-2-nitrophenyl)-3-heptyl-3-methylurea as an oily product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576335 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-0ed557f86cb647dda8e553acb0bf24a6 |
| Source note | uspto-grants-1996_11 |