Phenol → HCID 23370218, compound

HRID 1901110Notes

Reaction equation

HRID 1901110 reaction equation
C([Sn](CCCC)(CCCC)C1C=CN=CC=1)CCC.C([O:27][C:28]1[CH:33]=[C:32]([F:34])[CH:31]=[C:30](Br)[CH:29]=1)C1C=CC=CC=1.[C:36]1([OH:42])[CH:41]=[CH:40][CH:39]=CC=1>>[F:34][C:32]1[CH:33]=[C:28]([OH:27])[CH:29]=[C:30]([C:40]2[CH:41]=[CH:36][O:42][CH:39]=2)[CH:31]=1

Participants

4

Reactant 3

HCID 996Phenol2×HCID 27373184-(Tri-n-butylstannyl)pyridineHCID 112545161-(Benzyloxy)-3-bromo-5-fluorobenzene

Product 1

HCID 23370218HCID 23370218, compound

Procedure

Following the procedures described in Phenol 1, Steps 2 and 3, but substituting 3-tributylstannylfuran for 4-tributylstannylpyridine, and O-(3,4-dimethoxy)benzyl-3-bromo-5-fluorophenol from Phenol 2, Step 1 for O-benzyl-3-bromo-5-fluorophenol, the title compound was obtained as an oil.

Sources & evidence

ORD record
ord-f56c3ab635c240d98aa375913410679d
Source dataset
uspto-grants-1996_11
Patent number
US05576338

Reaction notes

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