3,5-Difluorobiphenyl → 3-Fluoro-5-(4-fluorophenyl)thiophenol

HRID 1901114Notes

Reaction equation

HRID 1901114 reaction equation
C[Si](C)(C)CC[S:5][C:6]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:9]=[C:8]([F:18])[CH:7]=1.[F:21]C1C=C(C2C=CC=CC=2)C=C(F)C=1>>[F:18][C:8]1[CH:7]=[C:6]([SH:5])[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([F:21])=[CH:14][CH:13]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 130223913,5-DifluorobiphenylHCID 57070644S-(2-Trimethylsilylethyl)-3-fluoro-5-phenylthiophenol

Product 1

HCID 233702153-Fluoro-5-(4-fluorophenyl)thiophenol

Procedure

Following the procedure described in Thiophenol 1, Step 3, but substituting S-(2-trimethylsilylethyl)-3-fluoro-5-(4-fluorophenyl)thiophenol for S-(2-trimethylsilylethyl)-3-fluoro-5-phenylthiophenol, the title compound was obtained as a liquid.

Sources & evidence

ORD record
ord-7f85c77d0e3a4ff6b65899aff9f48c70
Source dataset
uspto-grants-1996_11
Patent number
US05576338

Reaction notes

Loading…