Azobisisobutyronitrile → HCID 23370213, compound

Participants

Reaction Steps

To a solution of 2-cyano-4-(3-furyl)-7-methylquinoline (4.2 g) in refluxing CCl4 (400 mL) was added NBS (3.3 g) and AIBN (150 mg) portionwise. After 90 min., the mixture was cooled to r.t. and filtered through a pad of silica gel washing with CH2Cl2. The filtrate was concentrated and swished with Et2O for 15 h. The solid precipitate was collected and NMR analysis indicated that it contained 85% of the title compound. This material was used as such in the subsequent reactions.

Provenance & Evidence