Tetrahydrofuran → HCID 23370229, compound

Participants

Reaction Steps

A mixture of Pyridine 1 (80 mg), 2-cyano-4-(3-furyl)-7-hydroxy naphthalene (WO 94/00444, 111 mg), triphenylphosphine (146 mg) and di-t-butylazodicarboxylate (128 mg) in THF (7 mL) was stirred at r.t. for 4 h. The mixture was concentrated and the residue chromatographed (silica gel; hexane/EtOAc (5:1)) to provide the title compound as a solid, m.p. 131°-133° C.

Provenance & Evidence