HCID 131719721, compound → HCID 86750012, compound

Participants

Reaction Steps

1-(2,3-Dideoxy-5- O-tert-butyldiphenylsilyl-α-D-ribofuranosyl-5-(2-thienyl)uracil (0.15 g) was dissolved in tetrahydrofurane, 1M in tetrabutylammonium fluoride (3 ml) and stirred at ambient temperature for 1 hour. The solvent was evaporated and the product was purified by separation on preparative thin layer chromatography (silica-1 mm, ethyl acetate-methanol 9-1) to give 1, (2,3-dideoxy-α-D-ribofuranosyl)-5-(2-thienyl)uracil. TLC (silica, ethyl acetate-methanol 9-1) Rf 0.54.

Provenance & Evidence