4-Toluenesulfonyl chloride → HCID 86750013, compound

Participants

Reaction Steps

(Tolyl)diphenylsulphonium hexafluorophosphate (1.08 g, 2.57 mmol) and p-toluenesulphonyl chloride (2.38 g, 12.5 mmol) are dissolved with stirring in dichloromethane (40 ml), with cooling in ice-water. A solution of sodium peroxide (2.42 g, 31 mmol) in water (30 ml) is added dropwise over 20 minutes. After further stirring overnight the reaction mixture is diluted with dichloromethane and water. The mixture is allowed to separate and the dichloromethane containing layer collected, dried over magnesium sulphate, filtered and evaporated in vacuo. The resulting solid is slurried in water and collected. It is further washed with water and ether to yield (tolyl)diphenylsulphoxonium hexafluorophosphate (0.73 g, 65%) identical to authentic material.

Provenance & Evidence