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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1901387Generated: October 27, 2026

Glyphosate → N-tert-Butylglycine

https://huagongshe.com/reaction/1901387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlyphosateHCID 3496—
ReactantTert-ButylamineHCID 6385—
ReactantN-t-butyl-N-phosphonomethylglycineHCID 21917312—
ProductN-tert-ButylglycineHCID 414246—

Reaction Steps

Gaertner, U.S. Pat. No. 3,927,080, describes the production of glyphosate by acid hydrolysis and dealkylation of N-t-butyl-N-phosphonomethylglycine or its esters. Tertiary butyl amine is reacted with a bromoacetate ester to produce an ester of N-t-butyl-glycine, which is in turn reacted with formaldehyde and phosphorous acid to produce the N-t-butyl-N-phosphonomethylglycine precursor.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05578190
Source datasetuspto-grants-1996_11
ORD IDord-082993f8b855408eaa5512eb07cf6f38
Source noteuspto-grants-1996_11