反应详情

温度

35 °C

A solution of 4-aminothiophenol (7.00 g, 0.056 mol) in chloroform (75 ml) was added to a stirred, cooled (0° C.) solution of water (40 ml), chloroform (20 ml), calcium carbonate (6.60 g, 0.066 mol), and thiophosgene (6.95 g, 0.060 mol) at 0°-5° C. The mixture was heated at 35° C. for 1 hour and poured into water (50 ml) before separating the two layers. The organic layer was washed with hydrochloric acid (1%, 100 ml) and dried (MgSO4). The solvent was removed in vacuo to afford an orange semi-solid which was used in the next step without purification.

1. custombefore separating the two layers
2. washThe organic layer was washed with hydrochloric acid (1%, 100 ml)
3. dry with materialdried (MgSO4)
4. customThe solvent was removed in vacuo
5. customto afford an orange semi-solid which
6. customwas used in the next step without purification