Ethanol → HCID 22219052, compound

HRID 1901424Notes

Reaction equation

HRID 1901424 reaction equation
O[CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[CH2:11]([OH:13])[CH3:12]>>[C:5]1([N:4]2[CH:3]=[CH:2][CH:12]=[CH:11][O:13]2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 702EthanolHCID 31235N-(2-Hydroxyethyl)aniline

Product 1

HCID 22219052HCID 22219052, compound

Conditions

Temperature
80 °C

Procedure

0.271 g of P-(2-phenyl-2-chloro acetyl)dimethylaminobenzene (1 mmole) and 0.274 g of N-(2 hydroxy ethyl)aniline (2.0 mmole) were dissolved in 3 ml of dry ethanol and heated in a sealed tube at 80° C. for 8 hours. On cooling the product crystallized out as pale yellow needles, which was filtered and dried to yield 0.2 g of N-phenyl oxazine Compound 15.

Workup

  1. temperatureOn cooling the product
  2. customcrystallized out as pale yellow needles, which
  3. filtrationwas filtered
  4. customdried

Sources & evidence

ORD record
ord-5f72fd7b463b4e4b8a0587a185933461
Source dataset
uspto-grants-1996_11
Patent number
US05578498

Reaction notes

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