反应详情

To 20 ml of a 2-propanol solution of 1.59 of 3-(2-amino-2-methylpropoxy)-5-chloro-1,2-benzoisoxazole is added 20 ml of a dioxane solution (7.5N) of hydrogen chloride, and the crystals precipitated are collected by filtration, to obtain 1.62 g of colorless, crystalline 3-(2-amino-2-methylpropoxy)-5-chloro-1,2-benzoisoxazole hydrochloride having a melting point of 245.0°-246.0° C.

1. customthe crystals precipitated
2. filtrationare collected by filtration