HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 15383928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 15383948 | HCID 15383948 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15383928 | HCID 15383928 | 80.9% |
Reaction Steps
A procedure similar to that described in Example 1 was repeated, except that 0.96 g of 5-[4-{2(R)-[5(S)-(3-chlorophenoxymethyl)-2-oxooxazolidin-3-yl]propoxy}benzyl]-3-triphenylmethylthiazolidine-2,4-dione (prepared as described in Preparation 29), 4 ml of methylene chloride and 4 ml of trifluoroacetic acid were used, to give 0.52 g of the title compound having a melting point of 48° C. to 53° C. (softening) and having [α]D =+54.0° (methanol, c=1.000).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578620 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-a629f28b86c646af8afac6d22255909c |
| Source note | uspto-grants-1996_11 |