HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 15383930, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 15383950 | HCID 15383950 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15383930 | HCID 15383930 | 78.3% |
Reaction Steps
A procedure similar to that described in Example 1 was repeated, except that 286 mg of 5-[4-{2(S)-[5(S)-(3-chlorophenoxymethyl)-2-oxooxazolidin-3-yl]propoxy}benzyl]-3-triphenylmethylthiazolidine -2,4-dione (prepared as described in Preparation 41), 1 ml of trifluoroacetic acid and 1 ml of methylene chloride were used, to give 150 mg of the title compound, melting at 54° C. to 56° C. and having [α]D =+41.8° (methanol, c=0.975).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578620 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-c08ba2c0f31b4827a8d85910b15e45f5 |
| Source note | uspto-grants-1996_11 |