Tetrabutylammonium Fluoride → HCID 67741564, compound

Participants

Reaction Steps

A procedure similar to that described in Preparation was repeated, except that 0.88 g of 3-(2-t-butyldimethylsilyloxy-1(R)-methylethyl)-5(S)-(3-chlorophenoxymethyl)oxazolidin-2-one (prepared as described in Preparation 27), 6.6 ml of tetrabutylammonium fluoride (26% w/v in tetrahydrofuran) and 10 ml of anhydrous tetrahydrofuran were used, to give 0.58 g of the title compound having an Rf value of 0.45 (on silica gel thin layer chromatography, using ethyl acetate as the developing solvent) and having [α]D =+45.6° (methanol, c=1.000).

Provenance & Evidence