Tetrabutylammonium Fluoride → HCID 67741532, compound

Participants

Reaction Steps

A procedure similar to that described in Preparation 5 was repeated, except that 0.78 g of 3-[2-t-butyldimethylsilyloxy-1(S)-methylethyl]-5(R)-(3-chlorophenoxymethyl)oxazolidin-2-one (prepared as described in Preparation 35), 5.85 ml of tetrabutylammonium fluoride (26% w/v in tetrahydrofuran) and 10 ml of anhydrous tetrahydrofuran were used, to give 0.52 g of the title compound, melting at 92° C. to 94° C. and having [α]D =-47.8° (methanol, c=0.980).

Provenance & Evidence