HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 3-(8-Phenyloctyloxy)-2-hydroxypropylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 3-(8-Phenyloctyloxy)-2-hydroxypropylazide | HCID 21474713 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(8-Phenyloctyloxy)-2-hydroxypropylamine | HCID 21474729 | 88.7% |
Reaction Steps
A procedure similar to that described in Preparation 13 was repeated, except that 2.6 g of 3-(8-phenyloctyloxy)-2-hydroxypropylazide (prepared as described in Preparation 65), 0.65 g of lithium aluminum hydride and 80 ml of anhydrous tetrahydrofuran were used, to give 2.11 g of the title compound, melting at 50° C. to 54° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578620 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-c4eb1dabbc3c407ba96253284616737e |
| Source note | uspto-grants-1996_11 |