HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybiphenyl → 1-(Biphenyl-4-yloxy)-2,3-epoxypropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybiphenyl | HCID 7103 | — |
| Reactant | Epibromohydrin | HCID 18430 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(Biphenyl-4-yloxy)-2,3-epoxypropane | HCID 107325 | 83.3% |
Reaction Steps
A procedure similar to that described in preparation 46 was repeated, except that 4.00 g of 4-phenylphenol, 3.97 g of epibromohydrin, 1.27 g of sodium hydride (as a 55% by weight dispersion in mineral oil) and 80 ml of anhydrous dimethylformamide were used, to give 4.43 g of the title compound, melting at 80.2° to 82.9° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578620 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-cfff63133be84d1f80bcfd9589f90be5 |
| Source note | uspto-grants-1996_11 |