Tetrahydrofuran → HCID 21474816, compound

Participants

Reaction Steps

A procedure similar to that described in Preparation 5 was repeated, except that 4.38 g of ethyl 2-[5-(3-chlorophenoxymethyl)-2-oxooxazolidin-3-yl]pentanoate (less polar isomer), obtained as described in Preparation 96, 40 ml of anhydrous tetrahydrofuran, 0.39 g of lithium borohydride and 0.29 g of anhydrous methanol were used, to give 2.22 g of the title compound, melting at 79° C. to 81° C., from the less polar diastereomer.

Provenance & Evidence