HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl bromoacetate → Butyl 5-chloro-3-cyclohexyl-3-hydroxy-1-tosylindoline-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl bromoacetate | HCID 87883 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 5-Chloro-2-tosylaminophenyl cyclohexyl ketone | HCID 53778489 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | Butyl 5-chloro-3-cyclohexyl-3-hydroxy-1-tosylindoline-2-carboxylate | HCID 23368697 | — |
Reaction Steps
This compound is prepared by the reaction of butyl bromoacetate with 5-chloro-2-tosylaminophenyl cyclohexyl ketone, followed by cyclization in the presence of sodium methylate in butanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578633 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-fffce82ed2704359aee17a7df2b2c70c |
| Source note | uspto-grants-1996_11 |