HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 23368712, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Bromo-2-methylpropanamide | HCID 101235 | — |
| Reactant | N-[4-Chloro-2-(2-chlorobenzoyl)phenyl]-4-methylbenzene-1-sulfonamide | HCID 23368680 | — |
| Product | HCID 23368712 | HCID 23368712 | — |
Reaction Steps
8.4 g of 5,2'-dichloro-2-tosylaminobenzophenone are dissolved in 40 ml of DMF and treated with 0.7 g of 80% sodium hydride; after 15 minutes, 10 g of dimethylbromoacetamide, prepared in Example 1, are added and the mixture is stirred overnight at RT. The reaction medium is poured into water, the precipitate formed is filtered off and taken up with DCM and the solution is dried and concentrated. 9.2 g of the expected product are obtained after crystallization from isopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578633 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-29acb750a2bd4746abf09d8eb740e933 |
| Source note | uspto-grants-1996_11 |