HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-bromopropionate → Ethyl 3-(cyclopropylamino)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-bromopropionate | HCID 68320 | — |
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Ethyl 3-(cyclopropylamino)propanoate | HCID 13456042 | — |
Reaction Steps
B)a) 14.0 ml of ethyl 3-bromopropionate are added to a solution of 15.4 ml of cyclopropylamine in 100 ml of toluene and the reaction mixture is heated to 90° for 3 hours. Subsequently, the precipitated salt is filtered and the filtrate is distilled. There are obtained 9.5 g of N-cyclopropyl-β-alanine ethyl ester, Fab-MS: 157 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05578594 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-7eda87eb818f44c4be78798302983aca |
| Source note | uspto-grants-1996_11 |