HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malic Acid → HCID 12895722, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malic Acid | HCID 525 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Amino-N-(1-cyclohexyl-3-pyrrolidinyl)-N-methylbenzamide | HCID 59670 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12895722 | HCID 12895722 | — |
Reaction Steps
An ethanol solution containing 20.0 g. (0.067 mole) of 4-amino-N-(1-cyclohexyl-3-pyrrolidinyl)-N-methylbenzamide was treated with 4.94 g. (0.037 mole) of (-)-malic acid and the solution was refrigerated overnight. The crystalline material which separated (m.p. 147°-157° C.) was recrystallized twice from ethanol to give 5.0 g. crystals which melted at 162°-163° C. Rotation [α]D30 : -22.65 (water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04362667 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-23d80899f604462d8c8fe8d536e6eb39 |
| Source note | uspto-grants-1982_12 |