HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrobenzyl chloride → 2-[(2-Nitrophenyl)methyl]isoindole-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrobenzyl chloride | HCID 11921 | — |
| Reactant | Potassium phthalimide | HCID 3356745 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-[(2-Nitrophenyl)methyl]isoindole-1,3-dione | HCID 319537 | — |
Reaction Steps
The mixture of 54.0 of N-potassium phthalimide, 50.0 g of o-nitrobenzyl chloride and 120 ml of dimethylformamide is refluxed for 3 hours and poured into 900 ml of ice-water while stirring. After 30 minutes, it is filtered, and the residue washed with water, to yield the N-o-nitrobenzyl-phthalimide melting at 190°-209°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04362666 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-eead5c0713aa4ff4979b78921b536494 |
| Source note | uspto-grants-1982_12 |