HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 20515880, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 178527125 | HCID 178527125 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20515880 | HCID 20515880 | — |
Reaction Steps
To a slurry of 2.3 grams of the potassium salt (C) from Example III(a) in 10 ml methylene chloride and 5 ml DMF is added 1.5 ml p-chlorobenzoylchloride. This mixture is allowed to stir for 1 hour at room temperature. After this, saturated sodium bicarbonate solution is added and the product is extracted into methylene chloride. The organic layer is dried and concentrated in vacuo. The crude product (E) is crystallized from ether and hexane to yield 2 grams of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04362726 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-27680a8d11464c4e926c64ef7366b381 |
| Source note | uspto-grants-1982_12 |