HCID 12767925, compound → HCID 15575168, compound

Participants

Reaction Steps

5-Nitro-4',5'-dihydrospiro[benzo[b]thiophene-2(3H),3'(2'H)-furan]-3,2'-dione (1.0 g) was hydrogenated in the presence of 5% Pd-C (0.35 g) in acetic acid (100 ml) at room temperature under usual pressure of H2 gas with stirring. The catalyst was filtered off and the filtrate was evaporated in vacuo. The resulting residue was recrystallized from benzene to give 5-amino-4',5'-dihydrospiro[benzo[b]thiophene-2(3H),3'(2'H)-furan]-3,2'-dione as yellow needles, mp 187°-190° C. Anal. Calcd. for C11H9NO3S: C, 56.15; H, 3.86; N, 5.96. Found: C, 56.61; H, 3.73; N, 5.96.

Provenance & Evidence