HCID 15575169, compound → HCID 15575180, compound

HRID 1902250Notes

Reaction equation

HRID 1902250 reaction equation
[S:1]([C:5]1[CH:19]=[CH:18][C:8]2[S:9][C:10]3([C:16](=[O:17])[C:7]=2[CH:6]=1)[CH2:14][CH2:13]OC3=O)(=[O:4])(=[O:3])[NH2:2]>C(O)C>[S:1]([C:5]1[CH:19]=[CH:18][C:8]2[S:9][C:10]3([C:16](=[O:17])[C:7]=2[CH:6]=1)[CH2:14][CH2:13]3)(=[O:3])(=[O:4])[NH2:2]

Participants

3

Reactant 1

HCID 15575169HCID 15575169, compound

Product 1

HCID 15575180HCID 15575180, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

5-Sulfamoylspiro[benzo[b]thiophene-2(3H),1'-cyclopropan]-3-one was prepared by a similar procedure to that of Example 8 except for the use of 5-sulfamoyl-4',5'-dihydrospiro[benzo[b]thiophene-2(3H),3'(2'H)-furan]-3,2'-dione obtained in Reference Example 16. Pale yellow needles (from C2H5OH), mp 256°-258° C. (decomp.) Anal. Calcd. for C10H9NO3S2 : C, 47.04; H, 3.55; N, 5.49. Found: C, 47.18; H, 3.57; N, 5.44.

Workup

  1. customobtained in Reference Example 16

Sources & evidence

ORD record
ord-935f0a72576d45f4a0eb23282f2428bb
Source dataset
uspto-grants-1982_12
Patent number
US04362740

Reaction notes

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