Acetone → HCID 15575182, compound

HRID 1902252Notes

Reaction equation

HRID 1902252 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([S:7]([C:10]2[CH:24]=[CH:23][C:13]3[S:14][C:15]4([C:21](=[O:22])[C:12]=3[CH:11]=2)[CH2:19]CO[C:16]4=O)(=[O:9])=[O:8])[CH2:3][CH2:2]1.CC(C)=O>O>[O:1]1[CH2:6][CH2:5][N:4]([S:7]([C:10]2[CH:24]=[CH:23][C:13]3[S:14][C:15]4([C:21](=[O:22])[C:12]=3[CH:11]=2)[CH2:19][CH2:16]4)(=[O:8])=[O:9])[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 180AcetoneHCID 15575171HCID 15575171, compound

Product 1

HCID 15575182HCID 15575182, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5-Morpholinosulfonylspiro[benzo[b]thiophene-2(3H),1'-cyclopropan]-3-one was prepared by a similar procedure to that of Example 8 except for the use of 5-morpholinosulfonyl-4',5'-dihydrospiro[benzo[b]thiophene-2(3H),3'(2'H)-furan]3,2'-dione obtained in Reference Example 18. Colorless needles (from acetone --H2O), mp 162.5°-165° C. Anal. Calcd. for C14H15NO4S: C, 51.67; H, 4.65; N, 4.31. Found: C, 51.45; H, 4.55; N, 4.41.

Workup

  1. customobtained in Reference Example 18

Sources & evidence

ORD record
ord-95312b385f3f4ab8a75d7f23844356cc
Source dataset
uspto-grants-1982_12
Patent number
US04362740

Reaction notes

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