HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1,1-Trifluoro-2-isothiocyanatoethane → HCID 178485065, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1,1-Trifluoro-2-isothiocyanatoethane | HCID 13883777 | — |
| Reactant | HCID 178485066 | HCID 178485066 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178485065 | HCID 178485065 | — |
Reaction Steps
A mixture of 2,2,2-trifluoroethyl isothiocyanate (0.68 g.) and 2-amino-4-[2-(2-cyano-3-methylguanidino)-ethylthiomethyl]thiazole (1.08 g.) in dimethylformamide (5 ml.) was maintained at 60° for 4 hours and then evaporated to dryness. The residue was recrystallised from acetonitrile to give 2-[3-(2,2,2-trifluoroethyl)thioureido]-4-[2-(2-cyano-3-methylguanidino)ethylthiomethyl]thiazole, m.p. 157°-158°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04362728 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-e2a8844fae4c4b85b9e74d4df99d72be |
| Source note | uspto-grants-1982_12 |