HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 178485067, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 178503928 | HCID 178503928 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178485067 | HCID 178485067 | — |
Reaction Steps
A solution of 4-amino-2-[2-(3-cyano-2-methylisothioureido)ethylthiomethyl]pyrimidine (0.75 g.) in 33% w/v methylamine in ethanol (15 ml.) was left at room temperature for 18 hours. The solution was concentrated to 5 ml., cooled in ice, and the crystalline precipitate collected to give 4-amino-2-[2-(2-cyano-3-methylguanidino)ethylthiomethyl]pyrimidine (0.52 g.), m.p. 189°-190°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04362728 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-eee5d5b83a6a40d99c8e356e3fc4af14 |
| Source note | uspto-grants-1982_12 |