HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2-(2,2,2-Trifluoroethyl)guanidino]-2-(4-aminobutylthio)pyrimidine → HCID 178503915, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2-(2,2,2-Trifluoroethyl)guanidino]-2-(4-aminobutylthio)pyrimidine | HCID 21298746 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178503915 | HCID 178503915 | — |
Reaction Steps
Dimethyl (cyanoimido)dithiocarbonate (0.08 g.) was added to a solution of 4-[2-(2,2,2-trifluoroethyl)-guanidino]-2-(4-aminobutylthio)pyrimidine (0.17 g.) in acetonitrile (2 ml.) and the solution left at room temperature for 18 hours and then evaporated to dryness to give 4-[2-(2,2,2-trifluoroethyl)guanidino]-2-[4-(3-cyano-2-methylisothioureido)butylthio]pyrimidine, characterised as the hydrogen maleate m.p. 181°-183°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04362728 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-492ba00ca2a24f41a4d9e7fecebdecc3 |
| Source note | uspto-grants-1982_12 |