HRID1902338

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C([O-])Cc1ccccc1Nc1c(Cl)cccc1Cl.[Na+]

HCID5018304

Diclofenac sodium

C14H10Cl2NNaO2

结构：CCN(Cc1cc(C(=O)OCCN(C)CCCl)cc(Br)c1N)C1CCCCC1

HCID20516441

未命名化合物

PRODUCTS

生成物

结构：CCN(Cc1cc(C(=O)OCCN(C)CCOC(=O)Cc2ccccc2Nc2c(Cl)cccc2Cl)cc(Br)c1N)C1CCCCC1

HCID54519623

未命名化合物

PROCEDURE

实验过程

This compound was prepared from sodium 2-[(2,6-dichlorophenyl)-amino]-phenyl-acetate and N-{2-[4-amino-3-bromo-5-(N-ethyl-cyclohexylaminomethyl)-benzoyloxy]-ethyl}-N-(2-chloroethyl)-methylamine analogous to Example 8. Oil.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8fc4a968d3864666a15719c092c71715
来源数据集: uspto-grants-1982_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04362738
来源说明: uspto-grants-1982_12

反应 SMILES

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH2:16][C:17]([O-:19])=[O:18].[Na+].[NH2:21][C:22]1[C:37]([CH2:38][N:39]([CH:42]2[CH2:47][CH2:46][CH2:45][CH2:44][CH2:43]2)[CH2:40][CH3:41])=[CH:36][C:25]([C:26]([O:28][CH2:29][CH2:30][N:31]([CH3:35])[CH2:32][CH2:33]Cl)=[O:27])=[CH:24][C:23]=1[Br:48]>>[NH2:21][C:22]1[C:37]([CH2:38][N:39]([CH:42]2[CH2:47][CH2:46][CH2:45][CH2:44][CH2:43]2)[CH2:40][CH3:41])=[CH:36][C:25]([C:26]([O:28][CH2:29][CH2:30][N:31]([CH3:35])[CH2:32][CH2:33][O:18][C:17](=[O:19])[CH2:16][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[NH:9][C:3]2[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][C:4]=2[Cl:8])=[O:27])=[CH:24][C:23]=1[Br:48]