Diclofenac sodium → HCID 54542495, compound

HRID 1902347Notes

Reaction equation

HRID 1902347 reaction equation
[NH2:1][C:2]1[C:15]([CH2:16][N:17]([CH:20]2[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]2)[CH2:18][CH3:19])=[CH:14][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12]Cl)=[O:7])=[CH:4][C:3]=1[Br:27].[Cl:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([Cl:35])[C:30]=1[NH:36][C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=1[CH2:43][C:44]([O-:46])=[O:45].[Na+]>>[NH2:1][C:2]1[C:15]([CH2:16][N:17]([CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2)[CH2:18][CH3:19])=[CH:14][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][O:45][C:44](=[O:46])[CH2:43][C:38]2[CH:39]=[CH:40][CH:41]=[CH:42][C:37]=2[NH:36][C:30]2[C:29]([Cl:28])=[CH:34][CH:33]=[CH:32][C:31]=2[Cl:35])=[O:7])=[CH:4][C:3]=1[Br:27]

Participants

3

Reactant 2

HCID 5018304Diclofenac sodiumHCID 542831714-[4-amino-3-bromo-5-(N-ethyl-cycloheptylaminomethyl)-benzoyloxy]-n-butyl chloride

Product 1

HCID 54542495HCID 54542495, compound

Procedure

This compound was prepared from 4-[4-amino-3-bromo-5-(N-ethyl-cycloheptylaminomethyl)-benzoyloxy]-n-butyl chloride and sodium 2-[(2,6-dichlorophenyl)-amino]-phenylacetate analogous to Example 8.

Sources & evidence

ORD record
ord-1742cac69fb8458d8e1e81e10763932e
Source dataset
uspto-grants-1982_12
Patent number
US04362738

Reaction notes

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