Diclofenac sodium → HCID 70548214, compound

HRID 1902348Notes

Reaction equation

[NH2:1][C:2]1[C:15]([CH2:16][N:17]([CH2:24][CH2:25][CH3:26])[CH:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)=[CH:14][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12]Cl)=[O:7])=[CH:4][C:3]=1[Br:27].[Cl:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([Cl:35])[C:30]=1[NH:36][C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=1[CH2:43][C:44]([O-:46])=[O:45].[Na+]>>[NH2:1][C:2]1[C:15]([CH2:16][N:17]([CH2:24][CH2:25][CH3:26])[CH:18]2[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]2)=[CH:14][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][O:45][C:44](=[O:46])[CH2:43][C:38]2[CH:39]=[CH:40][CH:41]=[CH:42][C:37]=2[NH:36][C:30]2[C:29]([Cl:28])=[CH:34][CH:33]=[CH:32][C:31]=2[Cl:35])=[O:7])=[CH:4][C:3]=1[Br:27]

Participants

Reactant 2

HCID 5018304Diclofenac sodium

HCID 70549939HCID 70549939, compound

Product 1

HCID 70548214HCID 70548214, compound

Procedure

This compound was prepared from 4-[4-amino-3-bromo-5-(N-cyclohexyl-n-propylaminomethyl)-benzoyloxy]-n-butyl chloride and sodium 2-[(2,6-dichlorophenyl)-amino]-phenylacetate analogous to Example 8. Oil.

Sources & evidence

ORD record: ord-756ecf56d50141b0965c7fc660364005
Source dataset: uspto-grants-1982_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04362738

Reaction notes

Loading…