Diclofenac sodium → HCID 20516224, compound

HRID 1902353Notes

Reaction equation

[NH2:1][C:2]1[C:16]([CH2:17][NH:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[CH:15][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]Cl)=[O:7])=[CH:4][C:3]=1[Br:23].[Cl:24][C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([Cl:31])[C:26]=1[NH:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[CH2:39][C:40]([O-:42])=[O:41].[Na+]>>[NH2:1][C:2]1[C:16]([CH2:17][NH:18][C:19]([CH3:22])([CH3:21])[CH3:20])=[CH:15][C:5]([C:6]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][O:42][C:40](=[O:41])[CH2:39][C:34]2[CH:35]=[CH:36][CH:37]=[CH:38][C:33]=2[NH:32][C:26]2[C:25]([Cl:24])=[CH:30][CH:29]=[CH:28][C:27]=2[Cl:31])=[O:7])=[CH:4][C:3]=1[Br:23]

Participants

Reactant 2

HCID 5018304Diclofenac sodium

HCID 70528469HCID 70528469, compound

Product 1

HCID 20516224HCID 20516224, compound

Procedure

This compound was prepared from 5-(4-Amino-3-bromo-5-tert. butylaminomethyl-benzoyloxy)-n-pentyl chloride and sodium 2-[(2,6-dichlorophenyl)-amino]-phenylacetate analogous to Example 8.

Sources & evidence

ORD record: ord-3da00cf5555a4da895034ce8b44bd7c2
Source dataset: uspto-grants-1982_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04362738

Reaction notes

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