HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,6-Dibromohexane → 6-Phenoxyhexyl bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,6-Dibromohexane | HCID 12368 | — |
| Reactant | Phenolate Sodium | HCID 4445035 | — |
| Product | 6-Phenoxyhexyl bromide | HCID 142878 | 77% |
Reaction Steps
Preparation analogously to Example 38 by the reaction of sodium phenolate with 1,6-dibromohexane to give 6-phenoxy-1-bromohexane (b.p.11 =172°-5°; yield 77%), which is reacted with excess 5-amino-5-desoxy-1.4;3.6-dianhydro-L-iditol 2-nitrate. Isolation as hydrochloride. Yield, after recrystallisation from isopropanol: 53%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04363805 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-f472639537c04c3fa55e0c1542f63088 |
| Source note | uspto-grants-1982_12 |