HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,8-Dibromooctane → [(8-Bromooctyl)oxy]benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,8-Dibromooctane | HCID 78310 | — |
| Reactant | Phenolate Sodium | HCID 4445035 | — |
| Product | [(8-Bromooctyl)oxy]benzene | HCID 12959377 | 75% |
Reaction Steps
Preparation analogously to Example 38 by the reaction of sodium phenolate with 1,8-dibromooctane to give 8-phenoxy-1-bromooctane (b.p.11 =196°-202°; yield 75%) which is reacted with excess 5-amino-5-desoxy-1.4;3.6-dianhydro-L-iditol 2-nitrate. Isolation is hydrochloride. Yield, after recrystallisation from ethanol/isopropanol: 62%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04363805 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-9936a70066974ca4b92d0849113ca6bc |
| Source note | uspto-grants-1982_12 |