HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylamine → HCID 7864499, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylamine | HCID 7582 | — |
| Reactant | 2-Nitrobenzoic acid | HCID 11087 | — |
| Reactant | Chloromethylphthalimide | HCID 87154 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 7864499 | HCID 7864499 | 83% |
Reaction Steps
o-Nitrobenzoic acid (10.0 g) and dicyclohexylamine (11.0 g) were added in sequence to 100 ml DMF, more solvent being necessary to dissolve the resulting salt. N-(Chloromethyl)phthalimide was added and the mixture stirred for 24 hours. The product was precipitated out with water. Recrystallization from ethyl acetate/cyclohexane yielded 15.3 g (83%) of the ester, m.p. 159°-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04363865 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-81752663ad2146608199782dfaba1162 |
| Source note | uspto-grants-1982_12 |