Acetic Anhydride → HCID 70524341, compound

HRID 1902515Notes

Reaction equation

HRID 1902515 reaction equation
[C:1]1([CH2:7][C:8]([NH:10][CH:11]2[C:23](=[O:24])[N:13]3[CH:14]([C:20]([OH:22])=[O:21])[CH:15]([CH2:18][OH:19])[CH2:16][S:17][C@H:12]23)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:25](OC(=O)C)(=[O:27])[CH3:26]>CS(C)=O>[C:1]1([CH2:7][C:8]([NH:10][CH:11]2[C:23](=[O:24])[N:13]3[CH:14]([C:20]([OH:22])=[O:21])[C:15](=[CH:18][O:19][C:25](=[O:27])[CH3:26])[CH2:16][S:17][C@H:12]23)=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 70523673HCID 70523673, compound

Product 1

HCID 70524341HCID 70524341, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

7-(2-Phenylacetamido)-3-hydroxymethylcepham-4-carboxylic acid (4 g.), dimethylsulfoxide (20 ml) and acetic anhydride (20 ml.) were treated in a similar manner to that of Example 4 (2) to give 7-(2-phenylacetamido)-3-acetoxymethylenecepham-4-carboxylic acid (2 g.).

Sources & evidence

ORD record
ord-d13c5a8e10954ec2b8738630c51e0a55
Source dataset
uspto-grants-1982_12
Patent number
US04363807

Reaction notes

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