HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-Methylthio-1,5,10,10a-tetrahydrothiazolo[3,4-b]isoquinolinium iodide → (S)-3-[(3-methylisoquinol-8-yl)imino]-1,5,10,10a-tetrahydrothiazolo[3,4-b]isoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-Methylthio-1,5,10,10a-tetrahydrothiazolo[3,4-b]isoquinolinium iodide | HCID 12874874 | — |
| Reactant | 3-Methylisoquinolin-8-amine | HCID 20515638 | — |
| Product | (S)-3-[(3-methylisoquinol-8-yl)imino]-1,5,10,10a-tetrahydrothiazolo[3,4-b]isoquinoline | HCID 22822245 | 53.9% |
Reaction Steps
By following the procedure of Example 2, but using (S)-3-methylthio-1,5,10,10a-tetrahydrothiazolo[3,4-b]isoquinolinium iodide (8 g) and 8-amino-3-methylisoquinoline (3.5 g) as the starting materials, (S)-3-[(3-methylisoquinol-8-yl)imino]-1,5,10,10a-tetrahydrothiazolo[3,4-b]isoquinoline (4.1 g) is obtained in the form of pale yellow crystals, m.p.=156° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04363909 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-6c70ca65f03f42e0835a2e2f696a97ea |
| Source note | uspto-grants-1982_12 |