反应详情

温度

80 °C

A mixture of 5 gm of 2-chloro-4-nitro-1,3-diphenoxy-benzene, 10 ml of dioxane and 6 gm of 4-chlorobenzylamine was stirred for 12 hours at 80° C. Thereafter, the reaction mixture was evaporated, the residue was taken up in chloroform, the resulting solution was extracted with 1 N sodium hydroxide, and the organic phase was dried with sodium sulfate. The chloroform was distilled off, and the residue was recrystallized from ethanol, yielding 4.7 gm (82.7% of theory) of the title compound, m.p. 95°-96° C.

1. customThereafter, the reaction mixture was evaporated
2. extractionthe resulting solution was extracted with 1 N sodium hydroxide
3. dry with materialthe organic phase was dried with sodium sulfate
4. distillationThe chloroform was distilled off
5. customthe residue was recrystallized from ethanol