反应详情

温度

100 °C

A mixture of 3.41 gm of 2-chloro-4-nitro-1,3-diphenoxy-benzene, 5 ml of dioxane and 4 gm of 3-trifluoromethyl-benzylamine was stirred for 12 hours at 100° C. Thereafter, the reaction mixture was evaporated, the residue was taken up in chloroform, the resulting solution was extracted first with 2 N sodium hydroxide and then with 2 N hydrochloric acid, and the organic phase was dried with sodium sulfate. The chloroform was distilled off, leaving 4.0 gm (95% of theory) of the title compound as a viscous yellow oil.

1. customThereafter, the reaction mixture was evaporated
2. extractionthe resulting solution was extracted first with 2 N sodium hydroxide
3. dry with materialwith 2 N hydrochloric acid, and the organic phase was dried with sodium sulfate
4. distillationThe chloroform was distilled off