HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(p-Methoxyphenyl)-2-propanone → 4-Dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(p-Methoxyphenyl)-2-propanone | HCID 31231 | — |
| Reactant | Dimethylformamide diethylacetal | HCID 70913 | — |
| Product | 4-Dimethylamino-3-(4-methoxyphenyl)-3-buten-2-one | HCID 53990102 | — |
Reaction Steps
A stirred mixture of 1-(4-methoxyphenyl)-2-propanone (8.2 g) and dimethylformamide diethyl acetal (9.5 ml) was heated on an oil bath at 95°-100° C. for 30 minutes. Volatile material was removed under vacuum and the residue was crystallised from ether-petroleum spirit (40°-60° C.) to give the title compound (mp 56°-58° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04364956 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-6bde78fefc914eb1811916b39b25c556 |
| Source note | uspto-grants-1982_12 |