Ammonia → HCID 13091173, compound

HRID 1902652Notes

Reaction equation

HRID 1902652 reaction equation
[NH3:1].[CH3:2][O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[C:11](=[O:21])[CH:12]=[C:13]([C:16](OCC)=[O:17])[O:14][CH:15]=2)=[CH:6][CH:5]=1>C(O)C>[CH3:2][O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[C:11](=[O:21])[CH:12]=[C:13]([C:16]([NH2:1])=[O:17])[O:14][CH:15]=2)=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 13277716HCID 13277716, compound

Product 1

HCID 13091173HCID 13091173, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Cold concentrated ammonia solution (30%, 80 ml) was added to a stirred suspension of ethyl 5-(4-methoxyphenyl)-4-oxo-4H-pyran-2-carboxylate (12.4 g) in ethanol (120 ml) at 5°-10° C. The mixture was stirred for a further 30 minutes at 0°-5° C. then the solid title product was washed with water and dried (mp 262°-263° C. with decomposition).

Workup

  1. washthe solid title product was washed with water
  2. customdried (mp 262°-263° C. with decomposition)

Sources & evidence

ORD record
ord-387068af97664d629eb257c1d813d161
Source dataset
uspto-grants-1982_12
Patent number
US04364956

Reaction notes

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