HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Phenyl-2-tetrazol-5-yl-4H-pyran-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 4-oxo-5-phenyl-4H-pyran-2-carbonitrile | HCID 13091175 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Phenyl-2-tetrazol-5-yl-4H-pyran-4-one | HCID 178515804 | — |
Reaction Steps
A mixture of 4-oxo-5-phenyl-4H-pyran-2-carbonitrile (2.0 g), sodium azide (1.0 g) and ammonium chloride (0.8 g) in dimethylformamide (20 ml) was stirred at room temperature for an hour. Ice (20 g) was added and the clear solution was acidified with 2 N hydrochloric acid (20 ml) giving a pale solid which was recrystallised from ethanol to give the title product (mp 237°-238° C. with decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04364956 |
| Source dataset | uspto-grants-1982_12 |
| ORD ID | ord-d7ba1ee261e442f28c933b54c8b63a06 |
| Source note | uspto-grants-1982_12 |