Boron tribromide → HCID 13091182, compound

HRID 1902657Notes

Reaction equation

HRID 1902657 reaction equation
B(Br)(Br)Br.C[O:6][C:7]1[CH:25]=[CH:24][C:10]([O:11][C:12]2[C:13](=[O:23])[CH:14]=[C:15]([C:18]([O:20]CC)=[O:19])[O:16][CH:17]=2)=[CH:9][CH:8]=1>C(Cl)Cl.O>[OH:6][C:7]1[CH:8]=[CH:9][C:10]([O:11][C:12]2[C:13](=[O:23])[CH:14]=[C:15]([C:18]([OH:20])=[O:19])[O:16][CH:17]=2)=[CH:24][CH:25]=1

Participants

5

Reactant 2

HCID 25134Boron tribromideHCID 13277721HCID 13277721, compound

Product 1

HCID 13091182HCID 13091182, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6344DichloromethaneSolvent

Procedure

Boron tribromide (8.8 ml) was added dropwise to a stirred solution of ethyl 5-(4-methoxyphenoxy)-4-oxo-4H-pyran-2-carboxylate (4.35 g) in methylene chloride (50 ml) causing gentle reflux. The solution was heated under reflux for a further 2 hours, then cooled and carefully diluted with water (25 ml). The solid title product was recrystallised from water (mp 257°-258° C. with decomposition).

Workup

  1. temperatureThe solution was heated
  2. temperatureunder reflux for a further 2 hours
  3. temperaturecooled
  4. customThe solid title product was recrystallised from water (mp 257°-258° C. with decomposition)

Sources & evidence

ORD record
ord-cd49c4ae325040d99d413b0332aa7c10
Source dataset
uspto-grants-1982_12
Patent number
US04364956

Reaction notes

Loading…